1.
Protein Sci
; 31(1): 283-289, 2022 01.
Article
in English
| MEDLINE | ID: covidwho-1516798
ABSTRACT
The PDBsum web server provides structural analyses of the entries in the Protein Data Bank (PDB). Two recent additions are described here. The first is the detailed analysis of the SARS-CoV-2 virus protein structures in the PDB. These include the variants of concern, which are shown both on the sequences and 3D structures of the proteins. The second addition is the inclusion of the available AlphaFold models for human proteins. The pages allow a search of the protein against existing structures in the PDB via the Sequence Annotated by Structure (SAS) server, so one can easily compare the predicted model against experimentally determined structures. The server is freely accessible to all at http://www.ebi.ac.uk/pdbsum.
Subject(s)
Databases, Protein , Proteins/chemistry , SARS-CoV-2/chemistry , Viral Proteins/chemistry , Animals , COVID-19/virology , Humans , Models, Molecular , Protein Conformation , Protein Folding , Software
2.
Nat Med
; 27(10): 1666-1669, 2021 10.
Article
in English
| MEDLINE | ID: covidwho-1488036